Pathology and Current Treatment of the Alzheimers Disease Essay

Pathology and Current Treatment of the Alzheimers DiseaseIntroductionOne of the just about feared aspects of aging is the deterioration of the memory and cognitive function (dementia) that occurs among the elderly with increase frequency with advancing years. A significant proportion of otherwise wholesome elderly persons show a significant decline in cordial function later in life. It has been estimated that 10% of the population over the fester of 65 suffers from mild to moderate dementia and 4-5% suffer from severe dementia. The relative incidence of severe dementia rises from less than 1% at ages 65 to 70 to over 15% by age 85 (Terry and Katzman, 1983). In the unify States alone, Alzheimers disease (AD), which is the major ca map of senile dementia, afflicts several zillion people, and with the change magnitude longevity of the population, the number of such endurings requiring complete and continuous institutional care will rise to epidemic proportions. This paper will plan of attack to describe the Alzheimers Disease condition, both behaviorally and neuropathologically, and then look at traditional and current methods of treatment for patients of Alzheimers Disease.The onset of senile dementia is characterized by increasing impairment of memory of recent events such as what a patient had for breakfast an hour earlier, though a detailed recall of the removed(p) past may be essentially intact. Inevitably, the patients lose their cognitive abilities, that is, their abilities to read, write, calculate, and use language appropriately they cannot feed or dress themselves, they do not recognize their cause families, they get lost when only a go around distance from home, and ultimately do not even know their own names (R. Perry et al., 2000, C.J.A. Mouli... ...minimal and mild) Alzheimers Disease relationship to episodic and semantic memory impairment, Neuropsychologia, 383, 2000, p. 252-271Prasad, K.N., Hovland, A.R., Cole, W.C., Prasad, K.C., Nah reini, P., Edwards-Prasad, J., Andreatta, C.P. Multiple antioxidants in the prevention and treatment of Alzheimers Disease Analysis of biochemical rationale, Clinical Neuropharmacology, 231, 2000, p. 2-13Roses, A.D. Apolipoprotein E affects the rate of Alzheimers Disease expression b -amyloid burden is a secondary consequence dependent on apoE genetic constitution and duration of disease, J. Neuropathol. Exp. Neurol, 53, 1994, p. 429-437Terry, R.D., Katzman, R. Senile dementia of the Alzheimers type, Ann. Neurol., 14, 1983, p. 497-506van Leuven, F. Single and seven-fold transgenic mice as models for Alzheimers Disease, Progress in Neurobiology, 613, 2000, p. 305-312